During my PhD, I developed a cell-interface-deciphering lipid nanotablet that analyzes cancer cell interface using logic-gated assemblies of DNA-modified plasmonic nanoparticles on supported lipid bilayers (Nano Letters 2025, Small Methods 2025, Science Advances 2020). At KIST, I am working on tissue-mimetic liposomes for effective gene and drug delivery. Please visit my personal homepage for more information; www.sy-choi.com
Postdoctoral Researcher
Seoul, South Korea
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Ph.D.
Chemistry
Courses
Thesis: Programming Plasmonic Nanoparticle Interactions with DNA Reaction Pathways for Biological Computing and Nanobiosensor
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B.S.
Chemistry
Awarded By
Korea Foundation for Woman in Science, Engineering and Technology (WISET)
Awarded a prestigious fellowship to support advanced postdoctoral research in scientific and engineering fields.
Awarded By
Seoul National University
Recognized for outstanding academic performance and research potential with a scholarship supporting lecture and research activities.
Awarded By
Hanyang University
Received for consistently high academic achievement during undergraduate studies in 2017.
Awarded By
Hanyang University
Received for consistently high academic achievement during undergraduate studies in 2016.
Awarded By
Department of Chemistry, Hanyang University
Granted a scholarship funded by alumni, recognizing academic merit and potential in chemistry.
Published by
Submitted
Summary
So Young Choi†, Chang Sik Cho†, Seongchan Kim⁺, Hyunkyung Kim⁺, Ki Hun Kim*, Donghyun Jo* and Hyojin Lee*, "Vitreous-mimetic liposomes enable effective gene delivery to the eye via intravitreal injection", submitted.
Published by
Cell communication and signaling
Summary
Minsol Jeon, Daeun Kim, So Young Choi, Seoyoung Kim, Seongchan Kim, Hyojin Lee*, Hyunkyung Kim*, "Lysosomal targeting of liposomes with acidic pH and cathepsin B induces protein aggregate clearance", Cell communication and signaling, 23, 296 (2025).
Published by
Small methods
Summary
So Young Choi, Jieun Kim⁺¹, Eunho Song†, Eunhye Park, Jingrui Wu, Juyeon Yoo, Jwa-Min Nam *, “Design, Mechanisms, and Applications of DNA-Mediated Dynamically Reconfigurable Plasmonic Gold Nanostructures”, Small methods, 2500448 (2025).
Published by
Nano Letters
Summary
So Young Choi, Young Suk Yu, Eunhye Park, Sung Hee Baek and Jwa-Min Nam*, “Cell-Interface-Deciphering Lipid Nanotablet for Nanoparticle Logic Gate-Based Real-Time Single-Cell Analysis”, Nano Letters, 25, 7, 2725–2731 (2025).
Published by
Small Methods
Summary
Eunhye Park, So Young Choi⁺, Jieun Kim⁺, Niko Hildebrandt*, Jin Seok Lee*, Jwa-Min Nam*, "Nanotechnologies for the Diagnosis and Treatment of SARS-CoV-2 and Its Variants", Small Methods, 7, 2300034 (2023).
Published by
Science Advances
Summary
Sungi Kim, Namjun Kim, Jinyoung Seo, Jeong-Eun Park, Eun Ho Song, So Young Choi, Jieun Kim, Seungsang Cha, Ha H Park, Jwa-Min Nam*, "Nanoparticle-based computing architecture for nanoparticle neural networks.", Science Advances, 6, eabb3348 (2020).
DNA design, NUPACK, Plasmonic nanoparticle synthesis, Liposome synthesis, Supported lipid bilayer synthesis, In vitro experimentation, In vivo experimentation, Image processing, Python.
Programmable nanomaterials, Nanobiosensors, Nanobiocomputing, Drug delivery, Immunosynapse.
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Summary
Poster presentation on a novel approach for glioblastoma treatment using TMZ-encapsulating liposomes delivered via intra-cisterna magna.
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Summary
Poster presentation detailing a cell-interfaced lipid nanotablet for advanced analysis of cellular membrane proteins.
Programmable nanomaterials, Nanobiosensors, Nanobiocomputing, Drug delivery.
